The dissemination of CMV in urine of different group from Guangxi and the relationship between CMV infection and renal disease / 中华实验和临床病毒学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To detect Human Cytomegalovirus (HCMV) DNA in urine samples from the following groups: pregnant women, sick newborns, hospitalized nephropathy patients, renal transplant recipients and normal population. Preliminarily study the relationship of HCMV infection and renal disease.</p><p><b>METHODS</b>To detect HCMV DNA in morning urine samples by Real-time fluorescence quantitative PCR (FQ-PCR).</p><p><b>RESULTS</b>The positive rates of HCMV DNA in the urine of pregnant women,sick newborns, hospitalized nephropathy patients, renal transplant recipients and normal population are 8.18%, 3.45%, 18.54%, 25.42%, 0.56%.</p><p><b>CONCLUSION</b>The infection rates of HCMV in the urine of pregnant women and sick newborns are very high in Guangxi, it should take serious measures to prevent and control the situation. HCMV probably participate in the injury of kidney, and worsen the disease. It should be one of the causes of renal disease.</p>