Prevalence of sensitization to aeroallergens in 10 030 patients with allergic rhinitis / 中华耳鼻咽喉头颈外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the main inhaled allergens in patients with allergic rhinitis.</p><p><b>METHODS</b>Forty-three standardization allergens were used to perform skin prick test in 54 813 patients with chronic rhinitis. According to different gender and age groups, 10 030 patients with allergic rhinitis were divided into eight groups. The distributions of different allergens in the eight groups were analyzed.</p><p><b>RESULTS</b>(1) The most common four allergens in male patients with allergic rhinitis were Dermatophagoides farina (Der f), Dermatophagoides pteronyssinus (Der p), Mugwort and Blaterlia Germanica. Der f, Der p, Mugwort and Chenopodium album were the most common in female patients. (2) In all groups, patients with dual positive allergens were the most common, followed by triple positive allergens and single positive allergen. (3) In single positive allergen group, the top four allergen in male 3-17 year group were Der f, Der p, Alternaria tenuis and Mugwort. In other male groups, the most common positive allergen were Der f, Der p, Mugwort and Blaterlia Germanica. Meanwhile, the top four positive allergens in female 3-17 year group were Der f, Der p, Mugwort and Alternaria tenuis, in 18-39 year group were Der f, Der P, Mugwort and Dandelion, in 40-59 year group were Der f, Der p Mugwort and mixed tree 1, in ≥60 year group were Derf, Der P, mixed animal hair and Mugwort. (4) In dual positive allergens group, the most common allergen combination was Der f+Der p, followed by Alternaria tenuis in patient of 3-17 year group. (5) In triple positive allergens group, the most common allergen combination was Der f+Der p+Blaterlia Germanica, followed by Der f+Der p+mixed animal hair.</p><p><b>CONCLUSIONS</b>Dust mites, flowers pollen, herbs, Alternaria tenuis and Blaterlia Germanica were the most common allergens in patients with allergic rhinitis. However, the frequencies of the allergens were different in different age groups.</p>