Impact of viable myocardium assessed by 99Tcm-MIBI SPECT and 18F-FDG PET imaging on clinical outcome of patients with left ventricular aneurysm underwent revascularization / 中华心血管病杂志
Chinese Journal of Cardiology
; (12): 999-1003, 2008.
Artículo
en Chino
| WPRIM (Pacífico Occidental)
| ID: wpr-355845
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the impact of viable myocardium assessed by (99)Tc()m-MIBI SPECT and (18)F-fluorodeoxyglucose (FDG) PET imaging in patients with left ventricular aneurysm (LVA) underwent revascularization (RVS).</p><p><b>METHODS</b>Forty-six consecutive patients with LVA (mean LVEF 36% +/- 7%), underwent (99)Tc(m)-sestamibi SPECT and (18)F-FDG PET examinations and received RVS therapy, were followed-up for a mean period of 80 +/- 27 months. Viable myocardium in aneurysm was defined as perfusion-metabolism mismatch score (MMS) >/= 2.0. Patients were divided into four groups by aneurysm viability and aneurysmectomy. Group A1 (n = 8) viability-; Group A2 (n = 15) viability-, aneurysmectomy; Group B1 (n = 10) viability +; and Group B2 (n = 13) viability +, aneurysmectomy.</p><p><b>RESULTS</b>The cardiac event rates during follow up were similar among groups [A1 (25%, 2/8), B1 (40%, 6/15), A2 (20%, 2/10) and B2 (31%, 4/13; P > 0.05)]. After revascularization, LVEF was improved (> 10%) in groups A2, B1 and B2 (P < 0.05). Multivariate logistic regression analysis showed that LV-MMS (OR = 2.34, 95% CI 1.08 - 5.06, P < 0.05), distal vessel disease (OR = 0.008, 95% CI 0.001 - 0.560, P < 0.05) and nonaneurysm perfusion score (OR = 0.24, 95% CI 0.07 - 0.85, P < 0.05) were significantly associated with the improvement of LVEF after revascularization.</p><p><b>CONCLUSIONS</b>Long term cardiac events rate post revascularization was not affected by viable myocardium or aneurysmectomy in LVA patients. Viable myocardium in LVA patients was associated with better LVEF improvement after revascularization.</p>
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Diagnóstico por Imagen
/
Tomografía Computarizada de Emisión de Fotón Único
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Tecnecio Tc 99m Sestamibi
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Fluorodesoxiglucosa F18
/
Tomografía de Emisión de Positrones
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Aneurisma Cardíaco
/
Metabolismo
/
Miocardio
Tipo de estudio:
Estudio diagnóstico
Límite:
Anciano
/
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Cardiology
Año:
2008
Tipo del documento:
Artículo