Expression of gastrin receptor in HCC cell lines and tissues / 中华肝胆外科杂志
Chinese Journal of Hepatobiliary Surgery
; (12): 881-883, 2008.
Artículo
en Chino
| WPRIM (Pacífico Occidental)
| ID: wpr-397217
Biblioteca responsable:
WPRO
ABSTRACT
Objective To study the expression of gastrin receptor in 4 HCC cell lines and tis-sues and their relation to clinieopathological features. Methods Immunohistochemical staining of GR was performed for the 4 HCC cell lines and the paraffin sections of 25 HCC cases. The relationship be-tween the GR expression in HCC sections and the clinicopatho[ogical parameters were analyzed. Results Positive staining for GR in the 3 HCC SMMC-7721>HepG2>QGY-7701 cell lines and HCC tissues was observed. The expression rate of gastrin receptor was 56 % (14/25). However, there was no association between expression of GR and elinieopathologieal features such as age, gender and clini-cal stage etc except for tumor thrombosis. Concision GR exists in the HCC. Futher study is needed to identify whether GR is a applicable target for endocrine therapy in HCC.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Hepatobiliary Surgery
Año:
2008
Tipo del documento:
Artículo