Research progress of relationship between protein tyrosine phosphatase 1B and hematologic neoplasms / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
; (12): 376-379, 2015.
Article
en Zh
| WPRIM
| ID: wpr-465919
Biblioteca responsable:
WPRO
ABSTRACT
Tyrosine phosphorylation is a key post-translational mechanism that regulates cellular processes and maintains homeostasis.Aberrant changes in tyrosine phosphorylation are often associated with disease states such as metabolicdisorders,cancer and cardiovascular disease.Protein tyrosine phosphatases (PTPs) are the enzyme family that regulates protein phosphorylation level of tyrosine residues in the cellular processes and signaling ways.So far,scientists have discovered 112 kinds of human PTPs.Among them,PTP1B is widely and clearly studied.Recently,as an enzyme that play a role in oncogenesis,PTP1B has been wildey studied by scientists.Here,we highlight the relationship between protein tyrosine phosphatase 1B and hematologic neoplasms.
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1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Journal of Leukemia & Lymphoma
Año:
2015
Tipo del documento:
Article