Expression of MKK4 protein in nasopharyngeal carcinoma and their clinical sig-nificances / 中国免疫学杂志
Chinese Journal of Immunology
; (12): 1235-1238, 2015.
Artículo
en Chino
| WPRIM (Pacífico Occidental)
| ID: wpr-476760
Biblioteca responsable:
WPRO
ABSTRACT
Objective:
To investigate the expression of MKK 4 protein in the nasopharyngeal carcinoma and its clinical significance.Methods:
Immunohistochemical methods were employed to analyze MKK 4 positive expression intensity and positive cells in freshly collected nasopharyngeal carcinoma of both 90nasopharyngeal carcinoma cases and 20 chronic nasopharyngitis control.The clinical pathological characteristic were analyzed.Results:
The data obtained by MKK4 immunohistochemistry showed that the MKK 4 positive rate was higher in control group than in the NPC group (95.5%vs 75.6%,P0.05 ) .Conclusion:
Positive rate of MKK4 protein in nasopharyngeal carcinoma tissues is lower than in chronic nasopharyngitis.MKK4 protein expressions in nasopharyngeal carcinoma tissues negatively correlated with lymph node metastasis ,clincal stage ,invasive depth ,and TTP (Time to progression),but not with age,gender,location and tumor volume.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Immunology
Año:
2015
Tipo del documento:
Artículo