Recent advances for clinical applications of caffeine in premature infants / 中国小儿急救医学

ABSTRACT

Caffeine has been applied in clinic more than 30years,nowadays,which is one of the safe and effective drugs for the treatment of neonatal disease.It has been proved that caffeine can significantly re-duce the major acute neonatal morbidities include apnea of prematurity,bronchopulmonary dysplasia,severe retinopathy,patent ductus arteriosus with surgical ligation.Moreover,recent research also shown that caffeine can improve babies neurological outcome and lung function.This review summarized the latest progression in the pharmacological characteristics,clinical applications and untoward effect of caffeine.