Protein and C_(3b) Fc receptor expression of the macrophage in autotranspla ntated splenictissue / 中国普通外科杂志

ABSTRACT

Objective To investigate the f un ction of the autotransplanted splenic tissue. Method s 120 Kunming mice were randomly divided into two groups sham operation group and group of 50% autograft splenic tissue implantation in the om ental pouch after total splenectomy. Six months after, splenic transplants were removed, and C 3b and Fc receptor and the expression of protein on the macr ophages was assayed in the implanted splenic tissue. Results The expression of protein and the receptor on the mac rophage in transplants were similar with that in the normal group. Conclusion The function of the macrophages in t he implanted splenic tissue judged by the expression of protein and receptor is normal, the autotransplanted splenic tissue can fulfil the function of the norma l spleen.