Effects of inhibition of Kupffer cell and splenectomy on thioacetamide-induced hepatic injury / 中国病理生理杂志
Chinese Journal of Pathophysiology
; (12)2000.
Article
en Zh
| WPRIM
| ID: wpr-523685
Biblioteca responsable:
WPRO
ABSTRACT
AIM: To examine the effects of inhibition of Kupffer cell and splenectomy on intestinal endotoxemia and hepatic injury. METHODS: The hepatic injury model was established by treatment with thioacetamide (TAA). At the same time, inhibition of Kupffer cells by intravenous GdCl_3 and splenectomy were performed. Serum alanine aminotransferase (ALT), TNF-?, endotoxin content and phagocytic index were observed. RESULTS: In the TAA+GdCl_3 group, and TAA+splenectomy group, the endotoxin content was significently higher than that in normal and TAA group (P
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Pathophysiology
Año:
2000
Tipo del documento:
Article