Retrospective analysis of rhabdomyolysis in diabetic patients with ketoacidosis or hyperosmolar state / 中国医师进修杂志

ABSTRACT

Objective To determine the occurrence of rhabdomyolysis(RM) in the diabetic hyperosmolar hyperglycemic state.Methods Sixteen patients(9 men and 7 women) with diabetic hyperosmolar state were studied.Six of 16(37.50%) patients showed biochemical evidence of RM.The clinical and biochemical features of the patients with RM(group RM) and the patients without RM(group non-RM) were compared.Results Patients with RM showed a 30-fold increase in serum creatine phospholipase(CK) and 50-fold in myoglobin (Mb) when compared to the patients without RM.Significantly higher mean glucose level,serum sodium level and serum osmolality were found in patients with RM than in those without RM(P