Determination of 10 Kinds of Phthalates in Cosmetics by High Performance Liquid Chromatography / 环境与健康杂志

ABSTRACT

Objective To establish a high performance liquid chromatography method for simultaneous determination of 10 kinds of phthalates in cosmetics. Methods 10 kinds of phthalates were separated on a C18 column using methanol-water as mobile phase at a flow rate of 1.0 ml/min, 25℃ column temperature and 280 nm detection wave. Results The detection limit of 10 kinds of phthalates were 0.1-7 mg/L. The precision was less than 3.95% and recovery rates varied from 98.59% to 108.07%. Conclusion The experimental results show that the method is simple, precise and accurate and suitable to simultaneous determination of 10 kinds of phthalates in cosmetics.