Alterations of Myocardial Mitochondrial Function Subjected to Ischemia/Reperfusion Injury in Cats / 第二军医大学学报
Article
en Zh
| WPRIM
| ID: wpr-551056
Biblioteca responsable:
WPRO
ABSTRACT
The effect of myocardium subjected to 60 min ischemia and 60 min reperfusion on the level of lipid peroxides (LPO) and function of myocardial mitochondria and activity of superoxide dismutase (SOD) was studied in cat cardiopulmonary bypass. Myocardial mitochondrial function was slightly depressed after 60 min ischemia but significantly depressed after 60 min reperfusion. Increased lipid peroxides content and decreased SOD activity were observed at 60 min ischemia. After reperfusion, the SOD activity continued decreasing, but LPO elevated apparently. These results support a hypothesis that the free radicals may contribute to the myocardial mitochondrial reperfusion injury.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Academic Journal of Second Military Medical University
Año:
1982
Tipo del documento:
Article