Long-Term Outcome of Cystic Lesions in the Pancreas: A Retrospective Cohort Study
Gut and Liver
; : 493-500, 2012.
Artículo
en Inglés
| WPRIM (Pacífico Occidental)
| ID: wpr-57996
Biblioteca responsable:
WPRO
ABSTRACT
BACKGROUND/AIMS:
The management guidelines for cystic lesions of the pancreas (CLPs) are not yet well established. This study was performed to document the long-term clinical outcome of CLPs and provide guidelines for the management and surveillance of CLPs.METHODS:
In this retrospective cohort study, an additional follow-up was performed in 112 patients with CLPs enrolled from 1998 to 2004 during a previous study.RESULTS:
During follow-up for the median period of 72.3 months, the size of the CLPs increased in 18 patients (16.1%). Six of these patients experienced growth of their CLPs after 5 years of follow-up. Twenty-six patients underwent surgery during follow-up, and four malignant cysts were detected. The overall rate of malignant progression during follow-up was 3.6%. The presence of mural nodules or solid components was independently associated with the presence of malignant CLPs. Seven patients underwent surgery after 5 years of follow-up. The pathologic findings revealed malignancies in two patients. There was only one pancreas-related death during follow-up.CONCLUSIONS:
The majority of CLPs exhibit indolent behavior and are associated with a favorable prognosis. However, long-term surveillance for more than 5 years should be performed because of the potential for growth and malignant transformation in CLPs.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Páncreas
/
Quiste Pancreático
/
Pronóstico
/
Estudios Retrospectivos
/
Estudios de Cohortes
/
Estudios de Seguimiento
/
Historia Natural
Tipo de estudio:
Estudio de etiología
/
Guía de práctica clínica
/
Estudio de incidencia
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Humanos
Idioma:
Inglés
Revista:
Gut and Liver
Año:
2012
Tipo del documento:
Artículo