Study of clinical immunotherapy in children with allergic asthma and rhinitis / 国际检验医学杂志

ABSTRACT

Objective To investigate the clinical application of specific allergen immunotherapy (AIT)for the children with al-lergic asthma and rhinitis.Methods The in vitro specific allergen test system was adopted to detect allergen specific IgE and total IgE in children outpatients of the Children's Hospital.The children patients with dust mite allergy were divided into groups for con-ducting therapy.The immunotherapy group adopted the Dermatophagoides farinae drops for hypoglossis desensitization therapy, while the control group was performed the anti-allergic therapy by the common drugs.The clinical control indicator scores were per-formed after 6-months and 12-month therapy and at the same time the change of serum specific LgE was observed.Results Among 218 cases of allergy,114 cases(52.4%)were inhalation allergy and 101 cases (46.3%)were food allergy.98 cases of dust mite al-lergy accounted for 44.95% of the total allergy and 85.96% of the inhalation allergy.The difference in the curative effects between the AIT group and the control group had statistical significance(P <0.01).Conclusion Among 218 children cases of allergy,the dust mite allergy was maximum in the specific allergen detection;the hypoglossis specific immunotherapy has significant curative effect for the children with allergic asthma and rhinitis.