Discordant Congenital Cytomegalovirus Infection in Twins
Pediatric Infection & Vaccine
; : 65-70, 2017.
Artículo
en Inglés
| WPRIM (Pacífico Occidental)
| ID: wpr-68153
Biblioteca responsable:
WPRO
ABSTRACT
Cytomegalovirus (CMV) infection is one of the most common congenital infections. The first case of discordant congenital CMV infection in twins occurred in Korea. A 31-year-old woman became pregnant with twins (dichorionic-diamniotic). An elective caesarean section was performed at 37 weeks. The first baby was male, weighing 2,410 g with an Apgar score of 8/9. The second baby was female, weighing 1,380 g with an Apgar score of 5/8. She had experienced intrauterine growth retardation, and presented with microcephaly, micrognathia, and joint stiffness. During the work-up for discordant twins, the second baby's serum test was positive for CMV immunoglobulin M. Her urine, blood, and cerebrospinal fluid (CSF) were CMV polymerase chain reaction positive. The first baby's CMV tests were negative. Ophthalmologic exam and audiometry performed on the second baby showed CMV retinitis and bilateral sensorineural hearing loss. She was treated with intravenous ganciclovir. Currently, she is bed-ridden and has significant developmental delay. Although the causes of discordant congenital CMV infection in twins are unclear, this case shows that discordant congenital CMV infection should be considered in twins with significant differences in intrauterine growth or clinical symptoms after birth.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Puntaje de Apgar
/
Retinitis
/
Audiometría
/
Gemelos
/
Inmunoglobulina M
/
Ganciclovir
/
Líquido Cefalorraquídeo
/
Cesárea
/
Reacción en Cadena de la Polimerasa
/
Infecciones por Citomegalovirus
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
/
Embarazo
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Pediatric Infection & Vaccine
Año:
2017
Tipo del documento:
Artículo