EFFECT OF MICROENVIRENMENT ON LIPASE-CATALYZED ENANTIOSEL-ECTIVE AMMONOLYSIS OF (?) -?-METHYLBENZYL ACETATE / 微生物学通报

ABSTRACT

The effects of reaction media, water activity, temperature and pH on Novozym 435-catalyzed enantiose-lective ammonolysis of (?) -?-methylbenzyl acetate have been systematically explored. Novozym 435 showed high catalytic activity and enantioselectivity in hexane; the optimum temperature and the initial water activity were 25℃ and 0.33 respectively; The suitable reaction pH was in the range of 6.0 - 7.0.