Effects of Beraprost Sodium Evaluated by Digital Infrared Thermal Imaging in Diabetic Patients with Peripheral Arterial Disease / 대한족부족관절학회지
Journal of Korean Foot and Ankle Society
; : 105-110, 2018.
Artículo
en Coreano
| WPRIM (Pacífico Occidental)
| ID: wpr-717138
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE:
This study examined the effects of beraprost sodium on digital infrared thermal images in patients with peripheral arterial disease caused by type 2 diabetes mellitus. MATERIALS ANDMETHODS:
Twenty-five diabetic patients with peripheral arterial disease were treated with beraprost sodium in a prospective, multicenter, cohort study from February 2013 to December 2014. Beraprost sodium (40 μg) was administered orally 3 times daily (120 μg/day) for 6 months. The visual analogue scale (VAS) and digital infrared thermal imaging (DITI) were performed to compare the blood flow improvement between before and after dosing.RESULTS:
Among the 25 patients included in the evaluation, 22 patients completed the study. A significant increase in body temperature was observed in the front and left side, particularly in the plantar side in DITI compared to that before and after administration. An increase in body temperature was observed at the frontal part from 28.1℃±2.3℃ to 29.1℃±2.1℃ (p=0.021), at the left side from 27.8℃±2.4℃ to 28.6℃±1.9℃ (p=0.028), at the plantar part at 24.0℃±1.5℃, and at the plantar part at 27.1℃±2.4℃ (p < 0.01). The VAS decreased significantly from 5.4±1.3 to 2.7±2.0 after 6 months of treatment (p < 0.01).CONCLUSION:
Beraprost sodium is a safe and easy-to use oral medication for diabetes peripheral arterial disease. It can be expected to increase the blood flow and decrease the lower extremity pain statistically after being taken for 6 months.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Sodio
/
Temperatura Corporal
/
Estudios Prospectivos
/
Estudios de Cohortes
/
Extremidad Inferior
/
Diabetes Mellitus Tipo 2
/
Enfermedad Arterial Periférica
Tipo de estudio:
Ensayo clínico controlado
/
Estudio de etiología
/
Estudio de incidencia
/
Estudio observacional
/
Factores de riesgo
Límite:
Humanos
Idioma:
Coreano
Revista:
Journal of Korean Foot and Ankle Society
Año:
2018
Tipo del documento:
Artículo