Your browser doesn't support javascript.
loading
The Relation of Nonalcoholic Fatty Liver Disease to Metabolic Syndrome
Artículo en Coreano | WPRIM (Pacífico Occidental) | ID: wpr-76978
Biblioteca responsable: WPRO
ABSTRACT

BACKGROUND:

The aim of this study was to elucidate the relationship between nonalcoholic fatty liver disease diagnosed by ultrasonography and the metabolic syndrome defined by NCEP-ATP III criteria.

METHODS:

Sixty-nine adult male subjects with negligible alcohol consumption underwent an anthropometric and laboratory investigation. The ultrasound scan of the liver was performed to determine the presence and the severity of nonalcoholic fatty liver disease.

RESULTS:

Nonalcoholic fatty liver disease was diagnosed in 36 cases by ultrasound scan. According to the severity of nonalcoholic fatty liver, triglyceride, HDL- cholesterol, alanine aminotransferase, aspartate aminotrasnferase, fasting insulin level, HOMA-IR, and obesity related variables (body mass index, percent body fat, waist circumference) showed a significant difference. The independent variables which account for the severity of nonalcoholic fatty liver disease was waist circumference, and alanine aminotransferase which is a predictor of nonalcoholic steatohepatitis. The prevalence of metabolic syndrome was 41% vs 6.1% in nonalcoholic fatty liver group vs control group, respectively, and the odds ratio was 11.1 (95% CI 2.29~53.6). The prevalence of nonalcoholic fatty liver was increased with increasing the number of features of metabolic syndrome.

CONCLUSION:

Nonalcoholic fatty liver disease was closely related to the metabolic syndrome and the severity classification of nonalcoholic fatty liver by ultrasound scan could be useful to predict of the severity of insulin resistance, and the risk of nonalcoholic steatohepatitis.
Asunto(s)

Texto completo: Disponible Base de datos: WPRIM (Pacífico Occidental) Asunto principal: Triglicéridos / Consumo de Bebidas Alcohólicas / Resistencia a la Insulina / Oportunidad Relativa / Tejido Adiposo / Colesterol / Prevalencia / Ultrasonografía / Ayuno / Clasificación Tipo de estudio: Estudio diagnóstico / Estudio de etiología / Estudio de prevalencia / Estudio pronóstico Límite: Adulto / Humanos / Masculino Idioma: Coreano Revista: Journal of the Korean Academy of Family Medicine Año: 2004 Tipo del documento: Artículo
Texto completo: Disponible Base de datos: WPRIM (Pacífico Occidental) Asunto principal: Triglicéridos / Consumo de Bebidas Alcohólicas / Resistencia a la Insulina / Oportunidad Relativa / Tejido Adiposo / Colesterol / Prevalencia / Ultrasonografía / Ayuno / Clasificación Tipo de estudio: Estudio diagnóstico / Estudio de etiología / Estudio de prevalencia / Estudio pronóstico Límite: Adulto / Humanos / Masculino Idioma: Coreano Revista: Journal of the Korean Academy of Family Medicine Año: 2004 Tipo del documento: Artículo
...