Analysis of genetic polymorphisms of 21 autosomal short tandem repeat loci among Han Chinese from Quanzhou / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 384-387, 2019.
Article
en Zh
| WPRIM
| ID: wpr-772001
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE@#To analyze genetic polymorphisms of 21 autosomal short tandem repeat (STR) loci from Quanzhou Han Chinese groups using a GlobalFiler kit, and to assess its value for forensic practice.@*METHODS@#For 402 unrelated Han individuals, allelic frequencies of 21 autosomal STR loci were determined by using the GlobalFiler kit. Genetic parameters of the 21 STR loci were calculated.@*RESULTS@#No deviation from Hardy-Weinberg equilibrium was observed for the 21 loci. Most of the loci were highly polymorphic. Observed heterozygosity has ranged from 0.637 to 0.945, power of discrimination has ranged from 0.801 to 0.991, polymorphism information content has ranged from 0.570 to 0.940, power of exclusion was between 0.337 to 0.888, and match probability was between 0.009 to 0.199.@*CONCLUSION@#GlobalFiler kit has a high value for personal identification and paternity testing for Han Chinese from Quanzhou.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Polimorfismo Genético
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China
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Repeticiones de Microsatélite
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Pueblo Asiatico
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Frecuencia de los Genes
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Genética de Población
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
Zh
Revista:
Chinese Journal of Medical Genetics
Año:
2019
Tipo del documento:
Article