Inhibitors of aquaporin 1 and its role in tumor development and progression / 药学学报
Acta Pharmaceutica Sinica
; (12): 910-919, 2018.
Artículo
en Chino
| WPRIM (Pacífico Occidental)
| ID: wpr-779951
Biblioteca responsable:
WPRO
ABSTRACT
Aquaporin 1 (AQP1), the first water channel protein discovered among the aquaporin family, is a hydrophobic transmembrane protein involved in transcellular water movement. Recent evidence shows that AQP1 plays a role in tumor cell proliferation and migration, angiogenesis and tumor development and progression, representing a potential therapeutic target. In this review, we discuss the structures, functions and inhibitors of AQP1, as well as the involvement of AQP1 in tumor development and progression.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Acta Pharmaceutica Sinica
Año:
2018
Tipo del documento:
Artículo