A Case of Chronic Myeloid Leukemia with Multiple Chloromas Treated Successfully with Dasatinib / 계명의대학술지
Keimyung Medical Journal
; : 120-126, 2015.
Artículo
en Inglés
| WPRIM (Pacífico Occidental)
| ID: wpr-79179
Biblioteca responsable:
WPRO
ABSTRACT
Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of the primitive hematopoietic stem cells. CML is characterized by the overproduction of myeloid cells, which results in marked splenomegaly and leukocytosis. CML presented by multiple chloromas is extremely rare. Multiple chloromas in the skin and brain are quite rare as the initial presentation of CML. These rare manifestation should alert clinicians to include CML in the differential diagnosis of patients presenting with multiple non-pruritic skin nodules or neurologic symptoms. Dasatinib has promising therapeutic potential for managing intracranial leukemic disease. Here, we report the case of a patient who visited the hospital with multiple chloroma which is unusual presentation of CML, and treated with dasatinib successfully.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Piel
/
Esplenomegalia
/
Encéfalo
/
Células Madre Hematopoyéticas
/
Leucemia Mielógena Crónica BCR-ABL Positiva
/
Células Mieloides
/
Sarcoma Mieloide
/
Diagnóstico Diferencial
/
Dasatinib
/
Leucocitosis
Tipo de estudio:
Estudio diagnóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
Keimyung Medical Journal
Año:
2015
Tipo del documento:
Artículo