Advanced progress in classic genomic and non-genomic regulating mechanism mediated by retinoic acids in anti-cancer treatments / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 81-86, 2019.
Artículo
en Chino
| WPRIM (Pacífico Occidental)
| ID: wpr-813317
Biblioteca responsable:
WPRO
ABSTRACT
Retinoic acid, an active metabolite of vitamin A, exerts multiple effects on regulating embryonic development and inducing differentiation, proliferation, apoptosis as well as resistance in various cancer cells. Apart from the classic genomic action (binding to the nuclear receptors to regulate the expression of its downstream target genes), retinoic acids also play important roles in anti-cancer effect through non-genomic pathways (via extranuclear and non-transcriptional effects).
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Tretinoina
/
Diferenciación Celular
/
Apoptosis
/
Receptores de Ácido Retinoico
/
Genómica
/
Quimioterapia
/
Neoplasias
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Central South University(Medical Sciences)
Año:
2019
Tipo del documento:
Artículo