Van Wyk-Grumbach syndrome: A case report and
literature review / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 1366-1370, 2016.
Article
en Zh
| WPRIM
| ID: wpr-815082
Biblioteca responsable:
WPRO
ABSTRACT
Van Wyk-Grumbach syndrome (VWGS) is a rare complication of prolonged untreated juvenile hypothyroidism characterized by precocious puberty and enlarged multicystic ovaries. A 13-year-old girl visited our outpatient clinic due to menstrual irregularities. She had precocious puberty, pituitary hyperplasia and multiple cystic ovaries in addition to clinical signs of severe congenital hypothyroidism. After the initiation of L-thyroxine therapy, the symptoms were alleviated in a short time. This rare syndrome is easy to be misdiagnosed as pituitary and ovarian tumor. High degree of suspicion and timely diagnosis can prevent unnecessary surgical procedures because the symptoms can be reversed with thyroid hormone supplementation.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Quistes Ováricos
/
Ovario
/
Patología
/
Hipófisis
/
Pubertad Precoz
/
Síndrome
/
Tiroxina
/
Hipotiroidismo Congénito
/
Usos Terapéuticos
/
Diagnóstico
Tipo de estudio:
Diagnostic_studies
Límite:
Adolescent
/
Female
/
Humans
Idioma:
Zh
Revista:
Journal of Central South University(Medical Sciences)
Año:
2016
Tipo del documento:
Article