Rifampin-induced Pseudomembranous Colitis with Rectosigmoid Sparing
Clinical Endoscopy
; : 137-139, 2011.
Artículo
en Inglés
| WPRIM (Pacífico Occidental)
| ID: wpr-82697
Biblioteca responsable:
WPRO
ABSTRACT
Pseudomembranous colitis (PMC) is known to be associated with antibiotic treatment, but is not commonly related to antitubercular (anti-TB) agent, rifampin. PMC is frequently localized to rectum and sigmoid colon, which can be diagnosed with sigmoidoscopy. We report a case of rifampin-induced PMC with rectosigmoid sparing in a pulmonary tuberculosis patient. An 81-year-old man using anti-TB agents was admitted with a 30-day history of severe diarrhea and general weakness. On colonoscopy, nonspecific findings such as mucosal edema and erosion were found in sigmoid colon, whereas multiple yellowish plaques were confined to cecal mucosa only. Biopsy specimen of the cecum was compatible with PMC. Metronidazole was started orally, and the anti-TB medications excluding rifampin were readministerred. His symptoms remarkably improved within a few days without recurrence. Awareness of rectosigmoid sparing PMC in patients who develop diarrhea during anti-TB treatment should encourage early total colonoscopy.
Texto completo:
Disponible
Contexto en salud:
Enfermedades Desatendidas
Problema de salud:
Diarrea
/
Enfermedades Desatendidas
/
Tuberculosis
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Recto
/
Recurrencia
/
Rifampin
/
Colon Sigmoide
/
Tuberculosis Pulmonar
/
Biopsia
/
Enterocolitis Seudomembranosa
/
Ciego
/
Colonoscopía
/
Sigmoidoscopía
Límite:
Anciano
/
Anciano de 80 o más años
/
Humanos
Idioma:
Inglés
Revista:
Clinical Endoscopy
Año:
2011
Tipo del documento:
Artículo