Alkaloid constituents from the fruits of Flueggea virosa / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
; (6): 385-392, 2020.
Article
en En
| WPRIM
| ID: wpr-827231
Biblioteca responsable:
WPRO
ABSTRACT
Three new indole alkaloids, flueindolines A-C (1-3), along with nine known alkaloids (4-12), were isolated from the fruits of Flueggea virosa (Roxb. ex Willd.) Voigt. Compounds 1 and 2 are two new fused tricyclic indole alkaloids possessing an unusual pyrido[1, 2-a]indole framework, and 3 presents a rare spiro (pyrrolizidinyl-oxindole) backbone. Their structures with absolute configurations were elucidated by means of comprehensive spectroscopic analysis, chemical calculation, as well as X-ray crystallography. Chiral resolution and absolute configuration determination of the known compounds 4, 10, and 11 were reported for the first time. The hypothetical biogenetical pathways of 1-3 were herein also proposed.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
En
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Año:
2020
Tipo del documento:
Article