Determination of chemical constituents in Lonicera maackii with HPLC-DAD-ESI-Q-TOF/MS / 中草药

ABSTRACT

Objective: To identify and determine the main chemical constituents of Lonicera maackii, and to provide data support for the development and utilization of L. maackii. Methods: The chemical constituents of L. maackii were identified by HPLC-DAD-ESI-Q-TOF/MS and the main chemical constituents were determined by HPLC-DAD. Results: A total of 31 chromatographic peaks were detected and 19 chemical constituents were identified from L. maackii, and the contents of the 10 compounds (logaric acid, chlorogenic acid, loganin, morroniside, Secoxyloganin, rutin, hyperoside, luteoloside, chlorogenic acid A, and chlorogenic acid C) were determined. Conclusion: The contents of the main chemical constituents in the flower buds of L. maackii were higher than those in the blooming stage and yellow flowering stage. The contents of main components in L. maackii were similar to those of Lonicerae Japonicae Flos. The results of this study provide data support for the development and utilization of L. maackii.