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Application of an Insulin Analogue in Six Hypoglycemia-Prone Hemodialysis Patients with Type 2 Diabetes / 대한내과학회지
Korean Journal of Medicine ; : 647-653, 2012.
Artículo en Coreano | WPRIM (Pacífico Occidental) | ID: wpr-85854
Biblioteca responsable: WPRO
ABSTRACT
Day-to-day insulin requirements often change due to subtle variations in insulin metabolism in patients with type 2 diabetes undergoing hemodialysis. In such cases, intra-hemodialysis hypoglycemia frequently occurs and is a main factor interfering with the delivery of dialysis. As a result, it reduces the quality of life in patients undergoing hemodialysis. The long-acting insulin analogue glargine provides peakless, continuous release over 24 h that approximates a normal basal insulin pattern. Because it has no peak, its use in patients with diabetes undergoing hemodialysis would hypothetically be useful. Specifically, patients would be able to avoid intra-hemodialysis hypoglycemia without the necessity of skipping insulin administration on the day of hemodialysis and achieving adequate glucose control on other days. We recently experienced six cases that switched from treatment with intermediate-acting insulin to a long-acting insulin analogue, which provided better glycemic control by reducing hypoglycemia risk. Limited data are available in the literature concerning insulin analogue usage in patients with diabetes undergoing hemodialysis. Our experience suggests a large-scale prospective investigation is required on this issue.
Asunto(s)

Texto completo: Disponible Base de datos: WPRIM (Pacífico Occidental) Asunto principal: Calidad de Vida / Diálisis Renal / Insulina de Acción Prolongada / Diálisis / Insulina Glargina / Glucosa / Hipoglucemia / Insulina / Fallo Renal Crónico Aspecto: Preferencia del paciente Límite: Humanos Idioma: Coreano Revista: Korean Journal of Medicine Año: 2012 Tipo del documento: Artículo
Texto completo: Disponible Base de datos: WPRIM (Pacífico Occidental) Asunto principal: Calidad de Vida / Diálisis Renal / Insulina de Acción Prolongada / Diálisis / Insulina Glargina / Glucosa / Hipoglucemia / Insulina / Fallo Renal Crónico Aspecto: Preferencia del paciente Límite: Humanos Idioma: Coreano Revista: Korean Journal of Medicine Año: 2012 Tipo del documento: Artículo
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