Molecular epidemiological analysis of mycoplasma infection in female reproductive tract in Xi'an / 公共卫生与预防医学

ABSTRACT

Objective To analyze the molecular epidemiological characteristics of mycoplasma infection in female reproductive tract in Xi'an. Methods Women suspected to be infected with mycoplasma who were admitted to the gynecological outpatient department of Northwest Women's and Children's Hospital and underwent genital mycoplasma detection in the testing center from January 2018 to January 2019 were enrolled. General demographic characteristics and 16S rDNA results were collected. Results Among 174 women, 58 cases were positive for mycoplasma, with a detection rate of 33.33% (58/174). A total of 36 cases were positive for Ureaplasma urealyticum (Uu), with a detection rate of 20.69%. A total of 39 cases were positive for Mycoplasma hominis (Mh), with a detection rate of 20.09%. A total of 12 cases were positive for Mycoplasma gentiformis (Mg), with a detection rate of 6.90%. The positive rates in all groups included single or mixed infection cases. The positive rates of mycoplasma and Uu in patients with genital tract inflammation, pregnancy and menopause were higher than those in patients without reproductive tract inflammation, pregnancy or menopause (P0.05). None of these factors affected the positive rates of mycoplasma, Uu, Mn or Mg. Conclusion Women with reproductive tract mycoplasma infection were mainly caused by mycoplasma, Uu and Mh, which are symbiotic bacteria of female genital tract, and do not show the specificity of age, fertility, menopause and various inflammation of genital tract.