Cardiac functional alterations and its risk factors in elderly patients with obstructive sleep apnea syndrome free of cardiovascular disease / 南方医科大学学报
Journal of Southern Medical University
; (12): 1587-1592, 2020.
Article
en Zh
| WPRIM
| ID: wpr-880788
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE@#To evaluate the changes of cardiac structure and function and their risk factors in elderly patients with obstructive sleep apnea syndrome (OSA) without cardiovascular complications.@*METHODS@#Eighty-two elderly OSA patients without cardiovascular disease admitted between January, 2015 and October, 2016 were enrolled in this study. According to their apnea-hypopnea index (AHI, calculated as the average number of episodes of apnoea and hypopnoea per hour of sleep), the patients were divided into mild OSA group (AHI < 15) and moderate to severe OSA group (AHI ≥ 15). The demographic data and the general clinical data were recorded and fasting blood samples were collected from the patients on the next morning following polysomnographic monitoring for blood cell analysis and biochemical examination. Echocardiography was performed within one week after overnight polysomnography, and the cardiac structure, cardiac function and biochemical indexes were compared between the two groups.@*RESULTS@#Compared with those with mild OSA group, the patients with moderate to severe OSA had significantly higher hematocrit (0.22±0.08 @*CONCLUSIONS@#Cardiac diastolic function impairment may occur in elderly patients with moderate or severe OSA who do not have hypertension or other cardiovascular diseases, and the severity of the impairment is positively correlated with AHI.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Volumen Sistólico
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Índice de Severidad de la Enfermedad
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Enfermedades Cardiovasculares
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Factores de Riesgo
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Función Ventricular Izquierda
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Disfunción Ventricular Izquierda
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Apnea Obstructiva del Sueño
Tipo de estudio:
Etiology_studies
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Risk_factors_studies
Límite:
Aged
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Humans
Idioma:
Zh
Revista:
Journal of Southern Medical University
Año:
2020
Tipo del documento:
Article