Evaluation of Multidrug Resistant Loop-mediated Isothermal Amplification Assay for Detecting the Drug Resistance of / 生物医学与环境科学（英文）
Biomedical and Environmental Sciences
; (12): 616-622, 2021.
Artículo
en Inglés
| WPRIM (Pacífico Occidental)
| ID: wpr-887737
Biblioteca responsable:
WPRO
ABSTRACT
Objective@#To evaluate multidrug resistant loop-mediated isothermal amplification (MDR-LAMP) assay for the early diagnosis of multidrug-resistant tuberculosis and to compare the mutation patterns associated with the @*Methods@#MDR-LAMP assay was evaluated using 100 @*Results@#The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of MDR-LAMP were 85.5%, 93.6%, 96.7%, and 74.4% for the detection of resistance to isoniazid and rifampicin, respectively, and 80.5%, 92.3%, 98.6%, and 41.4% for the detection of @*Conclusion@#MDR-LAMP is a rapid and accessible assay for the laboratory identification of rifampicin and isoniazid resistance of
Texto completo:
Disponible
Contexto en salud:
Enfermedades Desatendidas
Problema de salud:
Enfermedades Desatendidas
/
Tuberculosis
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Oxidorreductasas
/
Fenotipo
/
Rifampin
/
Proteínas Bacterianas
/
ARN Polimerasas Dirigidas por ADN
/
ADN Bacteriano
/
Catalasa
/
Técnicas de Amplificación de Ácido Nucleico
/
Técnicas de Diagnóstico Molecular
/
Farmacorresistencia Bacteriana Múltiple
Tipo de estudio:
Estudio diagnóstico
/
Estudio de tamizaje
Idioma:
Inglés
Revista:
Biomedical and Environmental Sciences
Año:
2021
Tipo del documento:
Artículo
