Condensed tannins from roots of Indigofera stachyodes / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 4131-4138, 2021.
Article
en Zh
| WPRIM
| ID: wpr-888072
Biblioteca responsable:
WPRO
ABSTRACT
Eleven condensed tannins were isolated from the roots of Indigofera stachyodes by various column chromatography techniques including silica gel, octadecyl silica(ODS), Sephadex LH-20, and semi-preparative high performance liquid chromatography(HPLC). These compounds were identified on the basis of physicochemical properties, nuclear magnetic resonance(NMR) and mass spectrometry(MS) data as stachyotannin A(1), epicatechin-(2β→O→7,4β→8)-epiafzelechin-(4β→8)-catechin(2), cinnamtannin D1(3), cinnamtannin B1(4), epicatechin-(2β→O→7,4β→8)-epiafzelechin-(4α→8)-epicatechin(5), gambiriin C(6), proanthocyanidin A1(7), proanthocyanidin A2(8), aesculitannin B(9), proanthocyanidin A4(10), and procyanidin B5(11). Compound 1 is a new compound. Compounds 2-11 were isolated from Indigofera for the first time. Furthermore, compounds 1, 2, and 4-11 showed inhibitory effects on thrombin-induced ATP release in platelets.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Extractos Vegetales
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Espectroscopía de Resonancia Magnética
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Cromatografía Líquida de Alta Presión
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Indigofera
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Proantocianidinas
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2021
Tipo del documento:
Article