Systematic evaluation of Runing granule in the treatment of hyperplasia of mammary glands / 国际外科学杂志
International Journal of Surgery
; (12): 605-608,C1, 2021.
Artículo
en Chino
| WPRIM (Pacífico Occidental)
| ID: wpr-907490
Biblioteca responsable:
WPRO
ABSTRACT
Objective:
To assess the clinical effectiveness and safety of Runing granule for hyperplasia of mammary gland.Methods:
The databases such as the CNKI, Wanfang Data, VIP, CBM, Cochrane Library, Embase, PubMed and Web of Science are searched from the date of their establishment to June 2020. The main outcome measures were effective rate and incidence of adverse events. All randomized control trial (RCT) about the clinical effectiveness and safety of Runing granule single (single group) or combined with other treatment (combined group)/ other treatment (control group) for hyperplasia of mammary gland were included. Endnote software was used to manage literature, Excel software was used to extract data, quality assessment was conducted according to the methods of Cochrane Reviewers′ Handbook 5.1 recommend by the Cochrane Collaboration and Revman 5.3 software was used to perform Meta-analysis.Results:
Twelve RCT were included with total 2 447 patients. In terms of efficiency, Meta-analysis showed single group was better than control group ( RR=1.17, 95% CI 1.00-1.36, P=0.04), combined group was better than control group ( RR=1.35, 95% CI 1.10-1.67, P=0.005). In terms of adverse event rate, single group was lower than control group ( RR=0.18, 95% CI 0.09-0.34, P<0.01), combined group was better than control group( RR=0.33, 95% CI 0.20-0.56, P<0.01).Conclusion:
The usage of Runing granule single or combined with other treatment in the treatment of hyperplasia of mammary gland is more effective and the adverse reaction is lower.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Ensayo clínico controlado
Idioma:
Chino
Revista:
International Journal of Surgery
Año:
2021
Tipo del documento:
Artículo