Quality markers of Zingiberis Rhizoma Carbonisata before and after processing / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1765-1775, 2022.
Artículo
en Chino
| WPRIM (Pacífico Occidental)
| ID: wpr-928173
Biblioteca responsable:
WPRO
ABSTRACT
Based on the previous research results of our group and literature research, the chemical components, mechanisms, pharmacodynamics, and pharmacokinetics of Zingiberis Rhizoma Carbonisata were summarized to determine the quality markers(Q-markers) of Zingiberis Rhizoma Carbonisata and Zingiberis Rhizoma. Our research group has clarified the differential components of Zingiberis Rhizoma Carbonisata and Zingiberis Rhizoma, the meridian-warming hemostatic effect of Zingiberis Rhizoma Carbonisata, the related targets and pathways of the effect, the endogenous biomarkers of Zingiberis Rhizoma Carbonisata, and the hemodynamic processes of Zingiberis Rhizoma Carbonisata and Zingiberis Rhizoma. Moreover, based on high-performance liquid chromatography-diode array detector-electrospray ionization mass spectrometry(HPLC-DAD-ESIMS), a method for determining the content of Q-mar-kers was established. In conclusion, the study finally determined that gingerone, 6-shogaol, and diacetyl-6-gingerol were the Q-mar-kers of Zingiberis Rhizoma Carbonisata decoction pieces, and 6-gingerol, 8-gingerol, and 10-gingerol were Q-markers of Zingiberis Rhizoma decoction pieces. The result is expected to provide a reference for the establishment of quality standards for Zingiberis Rhizoma Carbonisata decoction pieces and Zingiberis Rhizoma decoction pieces.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Espectrometría de Masas
/
Medicamentos Herbarios Chinos
/
Extractos Vegetales
/
Biomarcadores
/
Cromatografía Líquida de Alta Presión
/
Zingiber officinale
/
Rizoma
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2022
Tipo del documento:
Artículo