Pharmaceutical care for a Crohn's disease patient with hypoalbuminemia and non-response to infliximab / 药学实践与服务
Journal of Pharmaceutical Practice and Service
; (12): 59-62, 2023.
Artículo
en Chino
| WPRIM (Pacífico Occidental)
| ID: wpr-953761
Biblioteca responsable:
WPRO
ABSTRACT
Objective To investigate the role of clinical pharmacists in individualized treatment and pharmaceutical care for a Crohn’s disease patient with non-response to infliximab. Methods The clinical pharmacist participated in the pharmaceutical care for a Crohn’s disease patient with hypoalbuminemia. Clinical pharmacists interpreted the blood concentration results of infliximab based on literature review, analyzed the pharmacokinetic process of drugs, and suggested that low serum albumin levels may cause the accelerated drug elimination and resulted in reduced drug concentration and secondary non-response. Results Clinical pharmacists assisted clinician adjusting the medication regimen and the patient recovered well after the new treatment plan. Conclusion With good understanding in medication pharmacokinetics and the blood test results, clinical pharmacists can help to solve the drug therapy related problems and establish an individual treatment plan to improve the safety and effectiveness of the biological medications.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Pharmaceutical Practice and Service
Año:
2023
Tipo del documento:
Artículo