Progress in omics research and preclinical models of gallbladder cancer / 中华外科杂志
Chinese Journal of Surgery
; (12): 260-264, 2023.
Article
en Zh
| WPRIM
| ID: wpr-970189
Biblioteca responsable:
WPRO
ABSTRACT
Gallbladder cancer(GBC)is one common type of bile tract cancers with poor prognosis. This review summarizes the recent development of studies about somatic mutation, molecular subtype, microenvironment heterogeneity, organoid, orthotopic model, patient-derived xenograft and clinical translation on GBC in aspects of genomic,transcriptome,single cell omics and clinical translation. We expect this review will provide new ideas on dissecting molecular mechanisms underlying the development and emerging chemoresistance of GBC following therapy and promote GBC precision medicine.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Pronóstico
/
Microambiente Tumoral
/
Neoplasias de la Vesícula Biliar
Límite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Surgery
Año:
2023
Tipo del documento:
Article