Research advances on the role of nuclear factor-erythroid 2-related factor 2 in wound healing / 中华烧伤杂志
Chinese Journal of Burns
; (6): 91-95, 2023.
Artículo
en Chino
| WPRIM (Pacífico Occidental)
| ID: wpr-971156
Biblioteca responsable:
WPRO
ABSTRACT
Wound healing is one of the common pathophysiological processes in the body. How to improve the condition of wound healing to promote rapid wound healing has always been a hotspot in research. Oxidative stress is one of the important factors affecting wound healing. Nuclear factor-erythroid 2-related factor 2 (Nrf2) is a classic antioxidant stress factor as well as a factor with great potential in facilitating wound healing. The activation of Nrf2 can regulate the downstream antioxidant stress elements and play roles of anti-apoptosis and cell homeostasis maintaining, which improves wound healing environment and promotes wound repair. This paper summarized the common agonists and inhibitors of Nrf2 and reviewed the roles of Nrf2 in promoting skin wound healing including diabetic ulcers, radiation injury, and ischemia-reperfusion injury, etc.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Cicatrización de Heridas
/
Estrés Oxidativo
/
Factor 2 Relacionado con NF-E2
/
Antioxidantes
Idioma:
Chino
Revista:
Chinese Journal of Burns
Año:
2023
Tipo del documento:
Artículo