Assessment on Application of 24 Y-STR Loci in Forensic Science / 法医学杂志
Journal of Forensic Medicine
; (6): 236-241, 2018.
Artículo
en Chino
| WPRIM (Pacífico Occidental)
| ID: wpr-984929
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVES@#To select a Y-STR marker system with strong haplotype identification ability, appropriate mutation rate and high compatibility and to assess its forensic application.@*METHODS@#The 24 Y-STR loci were tested by self-built fluorescent multiplex system, and the forensic assessment was conducted by 139 pairs of father-son samples collected in Jinan, Shandong province.@*RESULTS@#Totally 176 alleles were identified among the 24 Y-STR loci in the sample of 139 unrelated individuals labeled with father, and the gene diversity (GD) distributed between 0.083 7 (DYS645)-0.966 9 (DYS385a/b). According to the 24 Y-STR loci, 139 different haplotypes were detected from 139 unrelated male individuals labeled with father in Han population of Shandong province and with no shared haplotype observed. The overall haplotype diversity (HD) was 1 and the discrimination capacity (DC) was 1. A total of 5 one-step mutations events were observed among the 24 Y-STR loci in 139 pairs of father-son. The average mutation rate was 0.001 5 [95% CI (0.000 5, 0.003 5)].@*CONCLUSIONS@#The system of 24 Y-STR loci shows a strong individual recognition ability and low mutation rate in the population in Jinan, Shandong province, and it has good application value in forensic science.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Variación Genética
/
Haplotipos
/
China
/
Cromosomas Humanos Y
/
Ciencias Forenses
/
Grupos de Población
/
Alelos
/
Genética Forense
/
Tasa de Mutación
/
Genética de Población
Límite:
Humanos
/
Masculino
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
Journal of Forensic Medicine
Año:
2018
Tipo del documento:
Artículo