Assessment of long term outcomes after buccal mucosal graft urethroplasty: the impact of chronic kidney disease
Int. braz. j. urol
; 45(5): 981-988, Sept.-Dec. 2019. tab
Artigo
em Inglês
| LILACS
| ID: biblio-1040089
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT Objectives To compare and assess various outcomes and success of buccal mucosal graft urethroplasty (BMGU) in patients with CKD versus patients having normal renal function. Material and Methods This was a retrospective, single centre study, during period 2013 to 2017. Patients were grouped into two groups. Group 1 had patients with estimated Glomerular Filtration Rate (eGFR)>60mL/min/1.73m2 while group 2 had patients with eGFR <60mL/min/1.73m2. eGFR was calculated according to the MDRD equation. The two groups were compared with regard to various outcomes like length, location of stricture, technique of graft placement, intra-operative blood loss (haemoglobin drop), duration of hospital stay, post-operative complications and recurrence. Results A total of 223 patients were included in study with group 1 had 130 patients and group 2 had 93 patients. Mean age of patients with CKD were higher (47.49 years versus 29.13 years). The mean follow-up period was comparable between both groups (23.29 months and 22.54 months respectively). Patients with CKD had more post-operative Clavien Grade 2 or higher complications (p=0.01) and a greater recurrence rates (p<0.001) than in non-CKD patients. On multivariate analysis, age and CKD status was significant predictor of urethroplasty success (p=0.004) (OR= 14.98 (1.952-114.94, 95% CI). Conclusions CKD patients are more prone to post-operative complications in terms of wound infection, graft uptake and graft failure and higher recurrence rates following BMGU.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Procedimentos Cirúrgicos Urológicos
/
Uretra
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Estreitamento Uretral
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Insuficiência Renal Crônica
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Mucosa Bucal
Tipo de estudo:
Estudo de etiologia
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Estudo observacional
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Estudo prognóstico
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Fatores de risco
Limite:
Adolescente
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Adulto
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Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Int. braz. j. urol
Assunto da revista:
Urologia
Ano de publicação:
2019
Tipo de documento:
Artigo
País de afiliação:
Índia
Instituição/País de afiliação:
King George's Medical University/IN