Neuropathic pain in leprosy
In. Grzybowski, Andrzej; Virmond, Marcos da Cunha Lopes. Clinics in Dermatology: Leprosy: 2. New York, Elsevier, 2016. p.59-65, ilus, tab, graf.
Não convencional
em Inglês
| Sec. Est. Saúde SP, HANSEN, Hanseníase, SESSP-ILSLPROD, Sec. Est. Saúde SP, SESSP-ILSLACERVO, Sec. Est. Saúde SP
| ID: biblio-1096624
Biblioteca responsável:
BR191.1
Localização: BR191.1; 9527/S / BR191.1; 9543/S
ABSTRACT
Nerve impairment is a key clinical aspect of leprosy and may present the distribution of mononeuropathy or multiple nerve trunks, small cutaneous nerve fibers, and free nerve endings. The clinical range of leprosy is determined by individual cell-mediated immune response to infection that also may play a role in different types of pain syndromes in leprosy. Previous studies reported a high prevalence of neuropathic pain in leprosy. In an Ethiopian study with 48 patients, pure nociceptive pain was experienced by 43% of patients and pure neuropathic pain (NeP) by 11% of patients. In an Indian study, 21.8% of leprosy patients had pain with neuropathic characteristics. These rates underlie the need to develop tools for the early diagnosis and detection of infection and its complications, such as nerve damage and pain. In a larger sample with leprosy-associated NeP (n = 90), we have applied the Douleur Neuropathique en 4 questions (DN4) and found sensitivity = 97.1% and specificity = 57.9%. The high sensitivity of this tool in leprosy patients suggests that it could be a valuable tool to screen for neuropathic pain in this population and could be used as part of health care programs aimed at detecting, treating, and rehabilitating leprosy in endemic areas.
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Brasil
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Hanseníase
/
Doenças Negligenciadas
Base de dados:
HANSEN
/
Hanseníase
/
Sec. Est. Saúde SP
/
SESSP-ILSLACERVO
/
SESSP-ILSLPROD
Assunto principal:
Inquéritos e Questionários
/
Hanseníase
/
Neuralgia
Tipo de estudo:
Fatores de risco
/
Estudo de rastreamento
Limite:
Humanos
Idioma:
Inglês
Ano de publicação:
2016
Tipo de documento:
Não convencional
Instituição/País de afiliação:
Secretaria de Estado da Saúde/BR
/
University of São Paulo Mecical School/BR
/
University of São Paulo Medical School/BR