A living WHO guideline on drugs for COVID-19

Rochwerg, Bram; Agoritsas, Thomas; Lamontagne, François; Leo, Yee-Sin; Macdonald, Helen; Agarwal, Arnav; Zeng, Linan; Lytvyn, Lyubov; Appiah, John Adabie; Amin, Wagdy; Arabi, Yaseen; Blumberg, Lucille; Burhan, Erlina; Bausch, Frederique; Calfee, Carolyn S; Cao, Bin; Cecconi, Maurizio; Chanda, Duncan; Cooke, Graham; Du, Bin; Dunning, Jake; Geduld, Heike; Gee, Patrick; Hashimi, Madiha; Hui, David S; Kabra, Sushil; Kanda, Seema; Kawano-Dourado, Leticia; Kim, Yae-Jean; Kissoon, Niranjan; Kwizera, Arthur; Laake, Jon Henrik; Machado, Flavia R; Mahaka, Imelda; Manai, Hela; Mino, Greta; Nsutebu, Emmanuel; Pshenichnaya, Natalia; Qadir, Nida; Sabzwari, Saniya; Sarin,  Rohit; Sharland, Michael; Shen, Yinzhong; Ranganathan, Shalini Sri; Souza, Joao; Ugarte, Sebastian; Venkatapuram, Sridhar; Dat, Vu Quoc; Vuyiseka, Dubula; Wijewickrama, Ananda; Maguire, Brittany; Zeraatkar, Dena; Bartoszko, Jessica; Ge, Long; Brignardello-Petersen, Romina; Siemieniuk, Reed; Guyatt, Gordon; Diaz, Janet; Jacobs, Michael; Vandvik, Per Olav

Rochwerg, Bram; Agoritsas, Thomas; Lamontagne, François; Leo, Yee-Sin; Macdonald, Helen; Agarwal, Arnav; Zeng, Linan; Lytvyn, Lyubov; Appiah, John Adabie; Amin, Wagdy; Arabi, Yaseen; Blumberg, Lucille; Burhan, Erlina; Bausch, Frederique; Calfee, Carolyn S; Cao, Bin; Cecconi, Maurizio; Chanda, Duncan; Cooke, Graham; Du, Bin; Dunning, Jake; Geduld, Heike; Gee, Patrick; Hashimi, Madiha; Hui, David S; Kabra, Sushil; Kanda, Seema; Kawano-Dourado, Leticia; Kim, Yae-Jean; Kissoon, Niranjan; Kwizera, Arthur; Laake, Jon Henrik; Machado, Flavia R; Mahaka, Imelda; Manai, Hela; Mino, Greta; Nsutebu, Emmanuel; Pshenichnaya, Natalia; Qadir, Nida; Sabzwari, Saniya; Sarin, Rohit; Sharland, Michael; Shen, Yinzhong; Ranganathan, Shalini Sri; Souza, Joao; Ugarte, Sebastian; Venkatapuram, Sridhar; Dat, Vu Quoc; Vuyiseka, Dubula; Wijewickrama, Ananda; Maguire, Brittany; Zeraatkar, Dena; Bartoszko, Jessica; Ge, Long; Brignardello-Petersen, Romina; Siemieniuk, Reed; Guyatt, Gordon; Diaz, Janet; Jacobs, Michael; Vandvik, Per Olav.

BMJ ; 370: [1-14], Sept. 04, 2020.

Artigo em Inglês | BIGG - guias GRADE | ID: biblio-1129878

Biblioteca responsável: BR1.1

ABSTRACT

ABSTRACT

What is the role of drug interventions in the treatment of patients with covid-19? The latest version of this WHO living guidance focuses on remdesivir, following the 15 October 2020 preprint publication of results from the WHO SOLIDARITY trial. It contains a weak or conditional recommendation against the use of remdesivir in hospitalised patients with covid-19 The first version on this living guidance focused on corticosteroids. The strong recommendation for systemic corticosteroids in patients with severe and critical covid-19, and a weak or conditional recommendation against systemic corticosteroids in patients with non-severe covid-19 are unchanged.

Assuntos

Humanos; Corticosteroides/uso terapêutico; Antirretrovirais/uso terapêutico; COVID-19/tratamento farmacológico; Índice de Gravidade de Doença; Ivermectina/uso terapêutico; Lopinavir/uso terapêutico; Hidroxicloroquina/uso terapêutico; Fatores Imunológicos/uso terapêutico

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Texto completo: Disponível Coleções: Bases de dados temática Base de dados: BIGG - guias GRADE Assunto principal: Corticosteroides / Antirretrovirais / COVID-19 Tipo de estudo: Guia de prática clínica Idioma: Inglês Revista: BMJ Ano de publicação: 2020 Tipo de documento: Artigo

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