Epicardial adipose tissue and metabolic syndrome An update protocol for systematic review and meta-analysis
Medicine (Baltimore)
; 97(16): 0387, Apr. 2018. graf
Artigo
em Inglês
| Sec. Est. Saúde SP, CONASS, SESSP-IDPCPROD, Sec. Est. Saúde SP
| ID: biblio-1223409
Biblioteca responsável:
BR79.1
ABSTRACT
BACKGROUND:
The prevalence of metabolic syndrome (MetS) and MetS-related stroke is set to increase dramatically in coming decades. MetS is a complex disease that includes endothelial dysfunction, insulin resistance, diabetes, hypertension, ectopic obesity, and dyslipidaemia, and an increased risk of cardiovascular events. However, there are no systematic analyses, or well conducted meta-analyses to evaluate the relationship between epicardial adipose tissue (EAT) and (MetS). The aim of this study is to examine this association of EAT with MetS in different ages and sex.METHODS:
The update systematic review, and meta-analysis will be conducted using published studies that will be identified from electronic databases (ie, PubMed, EMBASE, Web of Science, and Google Scholar. Studies that firstly, examined the association between EAT and MetS, secondly, focus on cohort, case-control, and cross-sectional studies, thirdly, were conducted among in adults aged between 40 and 70 years, fourth, provided sufficient data for calculating ORs or relative risk with a 95% CI, fifth, were published as original articles written in English or other languages, and sixth, have been published until January year 2018 will be included. Study selection, data collection, quality assessment, and statistical syntheses will be conducted based on discussions among investigators.RESULTS:
Ethics approval was not required for this study because it was based on published studies. The results and findings of this study will be submitted and published in a scientific peer-reviewed journal. This study will provide a high quality synthesis on the association of EAT and MetS.CONCLUSION:
This systematic review will provide evidence to assess whether there is a strong association of EAT and MetS, and its components.
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Brasil
Base de dados:
CONASS
/
Sec. Est. Saúde SP
/
SESSP-IDPCPROD
Assunto principal:
Sexo
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Resistência à Insulina
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Acidente Vascular Cerebral
Tipo de estudo:
Estudo de etiologia
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Estudo observacional
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Estudo de prevalência
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Estudo prognóstico
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Fatores de risco
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Revisão sistemática
Aspecto:
Aspectos éticos
Idioma:
Inglês
Revista:
Medicine (Baltimore)
Ano de publicação:
2018
Tipo de documento:
Artigo
Instituição/País de afiliação:
Dante Pazzanese Institute of Cardiology, Department of Clinical Research/BR
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Department of AngioCardioNeurology, IRCCS Neuromed/IT
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Department of Clinical Research, HCFMUSP - University of São Paulo Medical School, Department of Cardiology/BR
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Department of Medicine, Tehran University of Medical Sciences/IR
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Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome/IT
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Department of Specialized and General Surgery, Fluminense Federal University,/BR
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Division of Cardiology, Duke University Medical Center, Department of Clinical Research/GB
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FOP Unicamp, Department of Clinical Research/BR
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Faculty of Medicine ABC, Department of Cardiology Santo André/BR
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Faculty of Medicine ABC, Department of Cardiology Santo André,/BR