Immunohistochemical observation of lysozyme in macrophages in leprosy
s.l; s.n; sep. 1978. 7 p. ilus, tab.
Não convencional
em Inglês
| Sec. Est. Saúde SP, HANSEN, Hanseníase, SESSP-ILSLACERVO, Sec. Est. Saúde SP
| ID: biblio-1240771
Biblioteca responsável:
BR191.1
Localização: [{"text": "BR191.1", "_a": "01308/s"}]
ABSTRACT
Lysozyme activities of skin granulomas of 24 patients in leprosy were studied. Lepra cells of all 15 lepromatous leprosy showed strong lysozyme activity in cytoplasma. In the specimens stained with lysozyme and Ziehl-Neelsen's carbolfuchsin double stain conspicuous lysozyme activity around M. leprae were observed. One borderline case was negative. Lysozyme of epithelioid cells and giant cells of 10 tuberculoid types were completely negative. These results suggest that lysozyme plays only a small role in the disposal of M. leprae in macrophages and other mechanisms than bacteriolytic function of lysozyme are responsible for the defence against these bacilli.
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Coleções:
Bases de dados nacionais
/
Brasil
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Hanseníase
/
Doenças Negligenciadas
Base de dados:
HANSEN
/
Hanseníase
/
Sec. Est. Saúde SP
/
SESSP-ILSLACERVO
Assunto principal:
Pele
/
Muramidase
/
Hanseníase
/
Macrófagos
/
Mycobacterium leprae
Limite:
Humanos
Idioma:
Inglês
Ano de publicação:
1978
Tipo de documento:
Não convencional
