Sero-prevalence of human T-lymphotrophic virus 1/2 among HIV-1 infected individuals in Ilorin, Nigeria
Afr. J. Clin. Exp. Microbiol
; 20(3): 202-208, 2019. ilus
Artigo
em Inglês
| AIM (África)
| ID: biblio-1256077
Biblioteca responsável:
CG1.1
ABSTRACT
Background:
HTLV1 or 2 coinfection in individuals infected with HIV1 can lead to increased morbidity. The shared routes of transmission of HTLV with HIV1 may increase the prevalence of HTLV among HIV1 infected population and subsequently affect patient's management.Methods:
Sera were collected from 144 HIV1 infected individuals attending the highly active antiretroviral therapy (HAART) clinic of the University of Ilorin Teaching Hospital between the months of May and August 2016. Sera were tested for antiHTLV IgM and IgG antibodies to HTLV1&2 using the sandwich enzymelinked immunosorbent assay.Results:
Out of the 144 participants tested, 47 (32.6%) and 37 (25.7%) were positive for HTLV IgG and IgM respectively. Twentyone participants (14.6%) had both IgG and IgM antibodies to HTLV1&2. Ten individuals were antiretroviral drug naïve out of which, four and six were positive to antiHTLV IgG and IgM respectively.Conclusion:
Findings from this study revealed that there is high seroprevalence of HTLV IgG and IgM antibodies among HIV1 seropositive individuals in Ilorin. The high rate of coinfection supports routine screening for HTLV1/2 co-infection among HIV1 infected individuals in Ilorin, Nigeria so that the purpose of HAART treatment and monitoring of patients to prevent progression to AIDS will not be aborted
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Base de dados:
AIM (África)
Assunto principal:
Nigéria
Tipo de estudo:
Estudo de prevalência
/
Fatores de risco
País/Região como assunto:
África
Idioma:
Inglês
Revista:
Afr. J. Clin. Exp. Microbiol
Ano de publicação:
2019
Tipo de documento:
Artigo