Phytochemical; Analgesic and Anti-Inflammatory Effects of the Ethylacetate Extract of the Leaves of Pseudocedrella Kotschyii
Afr. J. Tradit. Complement. Altern. Med. (Online)
; 5(1): 92-96, 2007.
Article
em En
| AIM
| ID: biblio-1256198
Biblioteca responsável:
CG1.1
ABSTRACT
Phytochemical screening was carried out on the ethylacetate portion of the ethanolic extract of the leaves of Pseudocedrella kotschyii and then evaluated for its analgesic (acetic acid-induced writhing) and anti-inflammatory (raw egg albumin-induced oedema) activities in mice and rats respectively. Phytochemical screening of the ethylacetate partition portion of ethanolic extract revealed the presence of flavonoids; glycosides and tannins as major chemical constituents. Alkaloids saponins; cardiac glycosides; steroids were not dictated in the extract. The ethylacetate extract (50 and 100 mg/kg i.p) exhibited significant activity (p0.05) against acetic acid-induced writhing in a dose dependent manner. In the anti-inflammatory activity the ethylacetate extract (50 and 100 mg/kg i.p.) caused a slight effect against the raw egg albumin-induced oedema. The effect was however observed not to be dose dependent. All these effects were compared with standard drug piroxicam (20 mg/kg i.p.)
Buscar no Google
Base de dados:
AIM
Assunto principal:
Folhas de Planta
/
Analgésicos
/
Anti-Inflamatórios
Idioma:
En
Revista:
Afr. J. Tradit. Complement. Altern. Med. (Online)
Ano de publicação:
2007
Tipo de documento:
Article