Effect of calcium lactate supplementation on cholesterol concentration in patients with hyperlipidaemia and previous viral hepatitis: a preliminary report
Cardiovasc. j. Afr. (Online)
; 19(2): 84-87, 2008. ilus
Artigo
em Inglês
| AIM (África)
| ID: biblio-1260374
Biblioteca responsável:
CG1.1
ABSTRACT
The aim of the study was to estimate the effect of calcium supplementation on cholesterol concentrations in patients with hyperlipidaemia and previous viral hepatitis. The study comprised 43 patients; aged 28 to 82 years (21 with type 2 hyperlipidaemia). The control group included 22 healthy subjects. After four weeks of a hypolipaemic diet (wash-out period); the patients with type 2 hyperlipidaemia were recruited to a group administered a complex preparation containing 170 mg of calcium lactate and 60 mg of vitamin C (Calcium C; Polfa-Lodz SA; Poland) at a dose of one tablet three times a day. After four weeks of active therapy; the concentration of total cholesterol (TC); low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG) decreased by 4; 6 and 8; respectively. Statistical significance was obtained for only TC (p = 0.03) when comparing the group of patients with hypercholesterolaemia before and after the therapy with the calcium preparation. A statistically insignificant increase of high-density lipoprotein cholesterol (HDL-C) of 1was observed. Within the four-week period of calcium supplementation at a dose of 510 mg/24 h; the total concentration of calcium decreased by 3; whereas the concentration of ionised calcium increased by 7. None of the obtained values was of statistical significance. In patients with type 2 hyperlipidaemia and previous viral hepatitis; a four-week supplementation of calcium in a calcium lactate preparation beneficially modified the lipid profile. it statistically significantly decreased the total cholesterol concentration by 4(p = 0.03); did not cause any significant changes in serum calcium concentration; was well tolerated and did not induce any side effects
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Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
Base de dados:
AIM (África)
Assunto principal:
Pacientes
/
Humanos
/
Cálcio
/
Colesterol
/
Hiperlipidemias
Idioma:
Inglês
Revista:
Cardiovasc. j. Afr. (Online)
Ano de publicação:
2008
Tipo de documento:
Artigo