COVID-19 autopsies from the Ga-East municipal and the 37 military hospitals, Accra, Ghana
Ghana Med. J. (Online)
; 54(4): 52-61, 2020. ilus
Artigo
em Inglês
| AIM (África)
| ID: biblio-1262313
Biblioteca responsável:
CG1.1
ABSTRACT
Introduction:
Since the declaration of COVID-19 by the World Health Organisation (WHO) as a global pandemic on 11th March 2020, the number of deaths continue to increase worldwide. Reports on its pathologic manifestations have been published with very few from the Sub-Saharan African region. This article reports autopsies on COVID19 patients from the Ga-East and the 37 Military Hospitals to provide pathological evidence for better understanding of COVID-19 in Ghana.Methods:
Under conditions required for carrying out autopsies on bodies infected with category three infectious agents, with few modifications, complete autopsies were performed on twenty patients with ante-mortem and/or postmortem RT -PCR confirmed positive COVID 19 results, between April and June ,2020.Results:
There were equal proportion of males and females. Thirteen (65%) of the patients were 55years or older with the same percentage (65%) having Type II diabetes and/or hypertension. The most significant pathological feature found at autopsy was diffuse alveolar damage. Seventy per cent (14/20) had associated thromboemboli in the lungs, kidneys and the heart. Forty per cent (6/15) of the patients that had negative results for COVID-19 by the nasopharyngeal swab test before death had positive results during postmortem using bronchopulmonary specimen. At autopsy all patients were identified to have pre-existing medical conditions.Conclusion:
Diffuse alveolar damage was a key pathological feature of deaths caused by COVID-19 in all cases studied with hypertension and diabetes mellitus being major risk factors. Individuals without co-morbidities were less likely to die or suffer severe disease from SARS-CoV-2
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Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Meta 3.8 Atingir a cobertura universal de saúde
Base de dados:
AIM (África)
Assunto principal:
Autopsia
/
Condições Patológicas, Sinais e Sintomas
/
COVID-19
/
Gana
/
Hospitais Militares
Tipo de estudo:
Estudo prognóstico
/
Fatores de risco
País/Região como assunto:
África
Idioma:
Inglês
Revista:
Ghana Med. J. (Online)
Ano de publicação:
2020
Tipo de documento:
Artigo