Rituximab-induced acute thrombocytopaenia in an African lupus patient: a case report
Ibom Medical Journal
; 13(3): 218-222, 2020.
Article
em En
| AIM
| ID: biblio-1262926
Biblioteca responsável:
CG1.1
ABSTRACT
Drug-induced acute thrombocytopaenia (DITP) is a complication of various medications resulting in a platelet count <50 x 109/L from prior normal levels. It typically occurs within 1-2 weeks postadministration but can occur rapidly within 1-3 days with previous exposure. Rituximab (an anti-CD20 antibody) used to treat many autoimmune cytopaenias, has been reported to cause thrombocytopaenia mostly in lymphoma patients. Reports in lupus are rare possibly because of off-label use. We hereby highlight the case of a 39-year old African lady who developed acute thrombocytopenia 12 days post-rituximab. Frequent monitoring of blood counts will enhance identification and treatment of this complication
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Base de dados:
AIM
Assunto principal:
Trombocitopenia
/
Rituximab
/
Doença Iatrogênica
Idioma:
En
Revista:
Ibom Medical Journal
Ano de publicação:
2020
Tipo de documento:
Article