Your browser doesn't support javascript.
loading
Guillain-Barré syndrome associated with SARS-CoV-2 infection: a scoping review
Medeiros, Kleyton Santos de; Macêdo, Luíza Thomé de Araújo; Souza, Wederson Farias de; Sarmento, Ayane Cristine; Costa, Ana Paula Ferreira; Gonçalves, Ana Katherine.
Afiliação
  • Medeiros, Kleyton Santos de; Universidade Federal do Rio Grande do Norte. Natal. BR
  • Macêdo, Luíza Thomé de Araújo; Centro Universitário do Rio Grande do Norte. Natal. BR
  • Souza, Wederson Farias de; Centro Universitário do Rio Grande do Norte. Natal. BR
  • Sarmento, Ayane Cristine; Universidade Federal do Rio Grande do Norte. Natal. BR
  • Costa, Ana Paula Ferreira; Universidade Federal do Rio Grande do Norte. Natal. BR
  • Gonçalves, Ana Katherine; Universidade Federal do Rio Grande do Norte. Natal. BR
Rev. Assoc. Med. Bras. (1992, Impr.) ; Rev. Assoc. Med. Bras. (1992, Impr.);67(2): 318-334, Feb. 2021. tab, graf
Article em En | LILACS | ID: biblio-1287811
Biblioteca responsável: BR1.1
ABSTRACT
SUMMARY

BACKGROUND:

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections can affect the nervous system, triggering problems such as the Guillain-Barre Syndrome (GBS), an association that can bring complications to the patient.

OBJECTIVE:

This scoping review aimed to clarify the clinical features and analyze patients with GBS associated with SARS-CoV-2 infection, looking at morbidity, mortality, and neurological outcomes. SEARCH STRATEGY The search was conducted through Medline, Web of Science, Embase, CINAHAL, Latin-American and Caribbean Literature in Health Sciences (LILACS), clinicaltrials.gov, SCOPUS, and the Cochrane Central Register of Controlled Trials. SELECTION CRITERIA Observational studies, published after 2019, describe patients with GBS associated with SARS-CoV-2 infection. There were no language restrictions while selecting the studies. DATA COLLECTION AND

ANALYSIS:

Three authors, Kleyton Santos de Medeiros, Luíza Thomé de Araújo Macêdo, and Wederson Farias de Souza, independently screened the search results using titles and abstracts. Duplicate studies were excluded. The same authors then went through the entire text to determine whether the studies met the inclusion criteria. Discrepancies were resolved by other reviewers, Ana Paula Ferreira Costa, Ayane Cristine Sarmento, and Ana Katherine Gonçalves. Finally, the selection of the studies was summarized in a PRISMA flow diagram. MAIN

RESULTS:

Main manifestations were fever, coughing, dyspnea, sore throat, ageusia, anosmia, and respiratory failure, in addition to paresthesia of the upper and lower limbs, tetraparesis, facial diplegia, areflexia, asthenia, mastoid pain, acute ataxia, fatigue, numbness, swallowing disorder, and moderate low back pain.

CONCLUSION:

Coronavirus disease 2019 (COVID-19) can trigger the GBS, despite the few studies on this topic. Patients had clinical manifestations of COVID-19 infection and neurological manifestations characterizing GBS.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Síndrome de Guillain-Barré / COVID-19 Tipo de estudo: Observational_studies / Risk_factors_studies / Systematic_reviews Idioma: En Revista: Rev. Assoc. Med. Bras. (1992, Impr.) Assunto da revista: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Síndrome de Guillain-Barré / COVID-19 Tipo de estudo: Observational_studies / Risk_factors_studies / Systematic_reviews Idioma: En Revista: Rev. Assoc. Med. Bras. (1992, Impr.) Assunto da revista: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil