Operational analysis of the national sickle cell screening programme in the Republic of Uganda
Afr. j. lab. med. (Online)
; 10(1): 1-8, 2021.
Article
em En
| AIM
| ID: biblio-1291595
Biblioteca responsável:
CG1.1
ABSTRACT
Background:
Sickle cell anaemia is a common global life-threatening haematological disorder. Most affected births occur in sub-Saharan Africa where children usually go undiagnosed and die early in life. Uganda's national sickle cell screening programme was developed in response to a 2014 sickle cell surveillance study that documented a high disease prevalence.Objective:
This study describes the temporal and financial aspects of Uganda's 20142019 sickle cell screening programme.Methods:
National sickle cell screening data from Uganda's Central Public Health Laboratories were used to calculate turn-around times (TATs) from sample collection to delivery, testing, and result reporting for blood samples collected from February 2014 to March 2019. The parameters affecting specific TATs were assessed. The exact programme expenditures were analysed to determine cost per test and per positive sickle cell disease case detected.Results:
A total of 278 651 samples were analysed. The median TAT from sample collection to laboratory receipt was 8 days (interquartile range [IQR] 612), receipt to testing was 3 days (IQR 17), and testing to result reporting was 6 days (IQR 312). Altogether, the sample continuum averaged 16 days (IQR 1124). Lower level healthcare facilities were associated with longer sample delivery TATs. Calendar months (January and December) and larger sample volumes impacted testing and result reporting TATs. The cost per test was $4.46 (United States dollars [USD]) and $483.74 USD per positive case detected.Conclusion:
Uganda's sickle cell screening programme is efficient and cost-effective. Universal newborn screening is the best strategy for detecting sickle cell anaemia in Uganda.Palavras-chave
Texto completo:
1
Base de dados:
AIM
Assunto principal:
Análise Custo-Benefício
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Instalações de Saúde
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Anemia Falciforme
Tipo de estudo:
Diagnostic_studies
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Risk_factors_studies
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Screening_studies
Idioma:
En
Revista:
Afr. j. lab. med. (Online)
Ano de publicação:
2021
Tipo de documento:
Article