Impact of duration of untreated psychosis on remission in first-episode schizophrenia in Thailand: a cohort study
Arch. Clin. Psychiatry (Impr.)
; Arch. Clin. Psychiatry (Impr.);48(3): 141-146, May-June 2021. tab
Article
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LILACS-Express
| LILACS
| ID: biblio-1349968
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT Background:
To scale up the services for first-episode schizophrenia in Thailand, it is essential to understand to what extent health care-seeking is delayed, and how much the delay affects the treatment outcome.Objectives:
To investigate the duration of untreated psychosis (DUP) and its impact on remission in first-episode schizophrenia across the country.Methods:
276 outpatients with a first-episode schizophrenia were followed for 6 months and assessed whether they fulfilled the criteria for remission at the follow-up. The proportion of those achieving remission was compared by the DUP. The impact of DUP on remission was estimated in multivariate analyses.Results:
At the follow-up, 83% (71/86) of patients who had met the criteria for symptomatic remission at the baseline achieved enduring remission, whereas 63% (119/190) of patients who had not met the criteria for symptomatic remission at baseline met it at the follow-up. The shorter the DUP, the higher the proportion of those who achieved symptomatic or enduring remission at the follow-up. The impact of DUP on symptomatic remission appeared to be significant after controlling for other factors influencing remission.Conclusion:
Since the DUP would influence remission of patients with schizophrenia, early detection and intervention services should be provided in Thailand.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Idioma:
En
Revista:
Arch. Clin. Psychiatry (Impr.)
Assunto da revista:
PSIQUIATRIA
Ano de publicação:
2021
Tipo de documento:
Article
/
Project document
País de afiliação:
Japão
/
Tailândia
País de publicação:
Brasil